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High-fidelity target sequencing of individual molecules identified using barcode sequences: de novo detection and absolute quantitation of mutations in plasma cell-free DNA from cancer patients

Circulating tumour DNA (ctDNA) is an emerging field of cancer research. However, current ctDNA analysis is usually restricted to one or a few mutation sites due to technical limitations. In the case of massively parallel DNA sequencers, the number of false positives caused by a high read error rate...

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Detalles Bibliográficos
Autores principales:	Kukita, Yoji, Matoba, Ryo, Uchida, Junji, Hamakawa, Takuya, Doki, Yuichiro, Imamura, Fumio, Kato, Kikuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535617/ https://www.ncbi.nlm.nih.gov/pubmed/26126624 http://dx.doi.org/10.1093/dnares/dsv010

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