Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix

BACKGROUND: Selective pressures at the DNA level shape genes into profiles consisting of patterns of rapidly evolving sites and sites withstanding change. These profiles remain detectable even when protein sequences become extensively diverged. A common task in molecular biology is to infer function...

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Detalles Bibliográficos
Autores principales: Ndhlovu, Andrew, Hazelhurst, Scott, Durand, Pierre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535666/
https://www.ncbi.nlm.nih.gov/pubmed/26269100
http://dx.doi.org/10.1186/s12859-015-0688-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535666/
https://www.ncbi.nlm.nih.gov/pubmed/26269100
http://dx.doi.org/10.1186/s12859-015-0688-8

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