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Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix
BACKGROUND: Selective pressures at the DNA level shape genes into profiles consisting of patterns of rapidly evolving sites and sites withstanding change. These profiles remain detectable even when protein sequences become extensively diverged. A common task in molecular biology is to infer function...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535666/ https://www.ncbi.nlm.nih.gov/pubmed/26269100 http://dx.doi.org/10.1186/s12859-015-0688-8 |