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Analysis of connexin expression during seizures induced by 4-aminopyridine in the rat hippocampus

BACKGROUND: In epilepsy, seizures are generated by abnormal synchronous activity in neurons. In the rat hippocampus (HIP), epileptiform activity has been found to be associated with gap junctions (GJs). GJs are formed by the combination of two hemichannels, each composed of six connexins. At low dos...

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Detalles Bibliográficos
Autores principales: Laura, Medina-Ceja, Xóchitl, Flores-Ponce, Anne, Santerre, Alberto, Morales-Villagrán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535691/
https://www.ncbi.nlm.nih.gov/pubmed/26268619
http://dx.doi.org/10.1186/s12929-015-0176-5