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Snai1 represses Nanog to promote embryonic stem cell differentiation

Embryonic stem cell (ESC) self-renewal and pluripotency is maintained by an external signaling pathways and intrinsic regulatory networks involving ESC-specific transcriptional complexes (mainly formed by OCT3/4, Sox2 and Nanog proteins), the Polycomb repressive complex 2 (PRC2) and DNA methylation...

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Detalles Bibliográficos
Autores principales: Galvagni, F., Neri, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535745/
https://www.ncbi.nlm.nih.gov/pubmed/26484184
http://dx.doi.org/10.1016/j.gdata.2015.03.007