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Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins

Arabidopsis High Mobility Group Box (HMBG) proteins were previously found associated with the interphase chromatin but not the metaphase chromosome. However, these studies are usually based on immunolocalization analysis involving paraformaldehyde fixation. Paraformaldehyde fixation has been widely...

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Detalles Bibliográficos
Autores principales: Li, Man-Wah, Zhou, Liang, Lam, Hon-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535772/
https://www.ncbi.nlm.nih.gov/pubmed/26270959
http://dx.doi.org/10.1371/journal.pone.0135033