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Identification of deleterious nsSNPs in α, μ, π and θ class of GST family and their influence on protein structure

GST family genes have a critical role in xenobiotic metabolism and drug resistance. Among the GST family the GST-μ, GST-π, GST-α and GST-θ are the most abundant classes and have a major role in the carcinogen detoxification process. Nevertheless the activity of these enzymes may differ due to polymo...

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Detalles Bibliográficos
Autores principales: Yadav, P., Chatterjee, A., Bhattacharjee, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535831/
https://www.ncbi.nlm.nih.gov/pubmed/26484073
http://dx.doi.org/10.1016/j.gdata.2014.03.004