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Identification of deleterious nsSNPs in α, μ, π and θ class of GST family and their influence on protein structure
GST family genes have a critical role in xenobiotic metabolism and drug resistance. Among the GST family the GST-μ, GST-π, GST-α and GST-θ are the most abundant classes and have a major role in the carcinogen detoxification process. Nevertheless the activity of these enzymes may differ due to polymo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535831/ https://www.ncbi.nlm.nih.gov/pubmed/26484073 http://dx.doi.org/10.1016/j.gdata.2014.03.004 |