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Genome-wide nucleosome occupancy and DNA methylation profiling of four human cell lines

DNA methylation and nucleosome positioning are two key mechanisms that contribute to the epigenetic control of gene expression. During carcinogenesis, the expression of many genes is altered alongside extensive changes in the epigenome, with repressed genes often being associated with local DNA hype...

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Detalles Bibliográficos
Autores principales: Statham, Aaron L., Taberlay, Phillippa C., Kelly, Theresa K., Jones, Peter A., Clark, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535833/
https://www.ncbi.nlm.nih.gov/pubmed/26484155
http://dx.doi.org/10.1016/j.gdata.2014.11.012