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Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms

The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesis and myeloid neoplasms, which resulted in a robus...

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Detalles Bibliográficos
Autores principales: Chalk, Alistair M., Liddicoat, Brian J.J., Walkley, Carl R., Singbrant, Sofie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535844/
https://www.ncbi.nlm.nih.gov/pubmed/26484093
http://dx.doi.org/10.1016/j.gdata.2014.06.022