IFNγ+ Treg in-vivo and in-vitro represent both activated nTreg and peripherally induced aTreg and remain phenotypically stable in-vitro after removal of the stimulus

BACKGROUND: IFNγ-producing CD4+CD25+Foxp3+CD127- Treg represent the first line of Treg during an immune response. In the present study we determined whether IFNγ+ Treg in-vivo and in-vitro are Helios-positive representing activated natural (nTreg) or Helios-negative representing adaptive Treg (aTreg...

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Detalles Bibliográficos
Autores principales: Daniel, Volker, Trojan, Karina, Adamek, Martina, Opelz, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535851/
https://www.ncbi.nlm.nih.gov/pubmed/26268522
http://dx.doi.org/10.1186/s12865-015-0111-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535851/
https://www.ncbi.nlm.nih.gov/pubmed/26268522
http://dx.doi.org/10.1186/s12865-015-0111-2

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