Cargando…

Global gene analysis identifying genes commonly regulated by the Ras/Raf/MEK and type I IFN pathways

Oncolytic viruses exploit alterations in cancer cells to specifically infect cancer cells but not normal healthy cells. Previous work has shown that oncogenic Ras interferes with interferon (IFN) signaling to promote viral replication. Furthermore, inhibition of the Ras/Raf/MEK/ERK pathway at the le...

Descripción completa

Detalles Bibliográficos
Autores principales: Komatsu, Y., Hirasawa, K., Christian, S.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535867/
https://www.ncbi.nlm.nih.gov/pubmed/26484185
http://dx.doi.org/10.1016/j.gdata.2015.03.012