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Global gene analysis identifying genes commonly regulated by the Ras/Raf/MEK and type I IFN pathways
Oncolytic viruses exploit alterations in cancer cells to specifically infect cancer cells but not normal healthy cells. Previous work has shown that oncogenic Ras interferes with interferon (IFN) signaling to promote viral replication. Furthermore, inhibition of the Ras/Raf/MEK/ERK pathway at the le...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535867/ https://www.ncbi.nlm.nih.gov/pubmed/26484185 http://dx.doi.org/10.1016/j.gdata.2015.03.012 |