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CTCF regulates positioning of the human cystic fibrosis gene in association with a histone deacetylase

The nuclear positioning of mammalian genes often correlates with their functional state. For instance, the human cystic fibrosis transmembrane conductance regulator (CFTR) gene associates with the nuclear periphery in its inactive state, but occupies interior positions when active. Treatment with th...

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Detalles Bibliográficos
Autor principal: Muck, Joscha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535900/
https://www.ncbi.nlm.nih.gov/pubmed/26484076
http://dx.doi.org/10.1016/j.gdata.2014.05.002