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Analysis of changes to mRNA levels and CTCF occupancy upon TFII-I knockdown

CTCF is a key regulator of nuclear chromatin structure, chromatin organization and gene regulation. The impact of CTCF on transcriptional output is quite varied, ranging from repression, to transcriptional pausing and transactivation. The multifunctional nature of CTCF is mediated, in part, through...

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Detalles Bibliográficos
Autores principales: Marques, Maud, Hernández, Rodrigo Peña, Witcher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535928/
https://www.ncbi.nlm.nih.gov/pubmed/26484167
http://dx.doi.org/10.1016/j.gdata.2014.09.012