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Analysis of changes to mRNA levels and CTCF occupancy upon TFII-I knockdown
CTCF is a key regulator of nuclear chromatin structure, chromatin organization and gene regulation. The impact of CTCF on transcriptional output is quite varied, ranging from repression, to transcriptional pausing and transactivation. The multifunctional nature of CTCF is mediated, in part, through...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535928/ https://www.ncbi.nlm.nih.gov/pubmed/26484167 http://dx.doi.org/10.1016/j.gdata.2014.09.012 |