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Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells

To study the role of WNT/β-catenin signaling in pancreatic adenocarcinoma, human BxPC-3 cell lines deficient of the central canonical WNT signaling protein β-catenin were established by using zinc-finger nuclease mediated targeted genomic disruption of the β-catenin gene (CTNNB1). Comparison of the...

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Detalles Bibliográficos
Autores principales: Olsen, Petter Angell, Lund, Kaja, Krauss, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535937/
https://www.ncbi.nlm.nih.gov/pubmed/26484203
http://dx.doi.org/10.1016/j.gdata.2015.04.010