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Pulmonary Haemodynamics in Sickle Cell Disease Are Driven Predominantly by a High-Output State Rather Than Elevated Pulmonary Vascular Resistance: A Prospective 3-Dimensional Echocardiography/Doppler Study

AIMS: Patients with sickle cell disease have significant morbidity and mortality. Pulmonary hypertension is suggested to be an important contributor but its nature and severity in these patients and how best to non-invasively assess it are controversial. We hypothesised that a high-output state rath...

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Detalles Bibliográficos
Autores principales: Mushemi-Blake, Sitali, Melikian, Narbeh, Drasar, Emma, Bhan, Amit, Lunt, Alan, Desai, Sujal R., Greenough, Anne, Monaghan, Mark J., Thein, Swee Lay, Shah, Ajay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535955/
https://www.ncbi.nlm.nih.gov/pubmed/26270484
http://dx.doi.org/10.1371/journal.pone.0135472