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Small molecule inhibition of FOXM1: How to bring a novel compound into genomic context

Deregulation of transcription factor (TF) networks is emerging as a major pathogenic event in many human cancers (Darnell, 2002 [1]; Libermann and Zerbini, 2006 [2]; Laoukili et al., 2007 [3]). Small molecule intervention is an attractive avenue to understand TF regulatory mechanisms in healthy and...

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Detalles Bibliográficos
Autores principales: Marsico, Giovanni, Gormally, Michael V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535965/
https://www.ncbi.nlm.nih.gov/pubmed/26484143
http://dx.doi.org/10.1016/j.gdata.2014.10.012