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Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia
BACKGROUND: A subset of the population receiving opioids for the treatment of acute and chronic clinical pain develops a paradoxical increase in pain sensitivity known as opioid-induced hyperalgesia. Given that opioid analgesics are one of few treatments available against clinical pain, it is critic...
Autores principales: | Oladosu, Folabomi A., Conrad, Matthew S., O’Buckley, Sandra C., Rashid, Naim U., Slade, Gary D., Nackley, Andrea G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535978/ https://www.ncbi.nlm.nih.gov/pubmed/26270813 http://dx.doi.org/10.1371/journal.pone.0135711 |
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