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The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells — A data description

A large number of breast cancers are characterized by amplification and overexpression of the chromosome segment surrounding the HER2 (ERBB2) oncogene. As the HER2 amplicon at 17q12 contains multiple genes, we have systematically explored the role of the HER2 co-amplified genes in breast cancer cell...

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Detalles Bibliográficos
Autores principales: Hongisto, Vesa, Aure, Miriam Ragle, Mäkelä, Rami, Sahlberg, Kristine Kleivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536024/
https://www.ncbi.nlm.nih.gov/pubmed/26484103
http://dx.doi.org/10.1016/j.gdata.2014.06.025