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Identification of TEL-AML1 (ETV6-RUNX1) associated DNA and its impact on mRNA and protein output using ChIP, mRNA expression arrays and SILAC

The contribution of the most common reciprocal translocation in childhood B-cell precursor leukemia t(12;21)(p13;q22) to leukemia development is still under debate. Direct as well as secondary indirect effects of the TEL-AML1 fusion protein are commonly recorded by using cell lines and patient sampl...

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Detalles Bibliográficos
Autores principales: Linka, Yvonne, Ginzel, Sebastian, Borkhardt, Arndt, Landgraf, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536161/
https://www.ncbi.nlm.nih.gov/pubmed/26484077
http://dx.doi.org/10.1016/j.gdata.2014.05.010