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Identification of TEL-AML1 (ETV6-RUNX1) associated DNA and its impact on mRNA and protein output using ChIP, mRNA expression arrays and SILAC
The contribution of the most common reciprocal translocation in childhood B-cell precursor leukemia t(12;21)(p13;q22) to leukemia development is still under debate. Direct as well as secondary indirect effects of the TEL-AML1 fusion protein are commonly recorded by using cell lines and patient sampl...
Autores principales: | Linka, Yvonne, Ginzel, Sebastian, Borkhardt, Arndt, Landgraf, Pablo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536161/ https://www.ncbi.nlm.nih.gov/pubmed/26484077 http://dx.doi.org/10.1016/j.gdata.2014.05.010 |
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