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Microarray profiling of L1-overexpressing endothelial cells reveals STAT3 activation via IL-6/IL-6Rα axis

We recently identified a novel role for the L1 transmembrane glycoprotein (also known as L1CAM or CD171) in the regulation of tumor angiogenesis and vessels stabilization. L1 overexpression in cultured endothelial cells of the lung (luECs) exerted a pleiotropic effect in that it regulated proliferat...

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Detalles Bibliográficos
Autores principales: Magrini, Elena, Cavallaro, Ugo, Bianchi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536177/
https://www.ncbi.nlm.nih.gov/pubmed/26484199
http://dx.doi.org/10.1016/j.gdata.2015.03.017