Predicting Hemagglutinin MHC-II Ligand Analogues in Anti-TNFα Biologics: Implications for Immunogenicity of Pharmaceutical Proteins

The purpose of this study was to evaluate the extent of overlapping immunogenic peptides between three pharmaceutical biologics and influenza viruses. Clinical studies have shown that subsets of patients with rheumatoid arthritis (RA) develop anti-drug antibodies towards anti-TNFα biologics. We post...

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Detalles Bibliográficos
Autores principales: Andrick, Benjamin J., Schwab, Alexandra I., Cauley, Brianna, O’Donnell, Lauren A., Meng, Wilson S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536234/
https://www.ncbi.nlm.nih.gov/pubmed/26270649
http://dx.doi.org/10.1371/journal.pone.0135451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536234/
https://www.ncbi.nlm.nih.gov/pubmed/26270649
http://dx.doi.org/10.1371/journal.pone.0135451

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