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Macroscopic modeling of mammalian cell growth and metabolism

We review major modeling strategies and methods to understand and simulate the macroscopic behavior of mammalian cells. These strategies comprise two important steps: the first step is to identify stoichiometric relationships for the cultured cells connecting the extracellular inputs and outputs. In...

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Detalles Bibliográficos
Autores principales: Ben Yahia, Bassem, Malphettes, Laetitia, Heinzle, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536272/
https://www.ncbi.nlm.nih.gov/pubmed/26198881
http://dx.doi.org/10.1007/s00253-015-6743-6