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Rewiring of an Epithelial Differentiation Factor, miR-203, to Inhibit Human Squamous Cell Carcinoma Metastasis

Metastatic colonization of distant organs underpins the majority of human-cancer-related deaths, including deaths from head and neck squamous cell carcinoma (HNSCC). We report that miR-203, a miRNA that triggers differentiation in multilayered epithelia, inhibits multiple postextravasation events du...

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Detalles Bibliográficos
Autores principales: Benaich, Nathan, Woodhouse, Samuel, Goldie, Stephen J., Mishra, Ajay, Quist, Sven R., Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536294/
https://www.ncbi.nlm.nih.gov/pubmed/25284788
http://dx.doi.org/10.1016/j.celrep.2014.08.062