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Granules Harboring Translationally Active mRNAs Provide a Platform for P-Body Formation following Stress

The localization of mRNA to defined cytoplasmic sites in eukaryotic cells not only allows localized protein production but also determines the fate of mRNAs. For instance, translationally repressed mRNAs localize to P-bodies and stress granules where their decay and storage, respectively, are direct...

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Detalles Bibliográficos
Autores principales: Lui, Jennifer, Castelli, Lydia M., Pizzinga, Mariavittoria, Simpson, Clare E., Hoyle, Nathaniel P., Bailey, Kathryn L., Campbell, Susan G., Ashe, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536303/
https://www.ncbi.nlm.nih.gov/pubmed/25437551
http://dx.doi.org/10.1016/j.celrep.2014.09.040