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Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis

Tumor heterogeneity can create a unique symbiotic tumor microenvironment. Earlier, we showed that clonal evolution in mouse small cell lung cancer (SCLC) can result in subclones that, upon cografting, endow the neuroendocrine tumor cells with metastatic potential. We now show that paracrine signalin...

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Detalles Bibliográficos
Autores principales: Kwon, Min-chul, Proost, Natalie, Song, Ji-Ying, Sutherland, Kate D., Zevenhoven, John, Berns, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536306/
https://www.ncbi.nlm.nih.gov/pubmed/26215568
http://dx.doi.org/10.1101/gad.262998.115