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Highly sampled tetranucleotide and tetraloop motifs enable evaluation of common RNA force fields

Recent modifications and improvements to standard nucleic acid force fields have attempted to fix problems and issues that have been observed as longer timescale simulations have become routine. Although previous work has shown the ability to fold the UUCG stem–loop structure, until now no group has...

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Detalles Bibliográficos
Autores principales: Bergonzo, Christina, Henriksen, Niel M., Roe, Daniel R., Cheatham, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536319/
https://www.ncbi.nlm.nih.gov/pubmed/26124199
http://dx.doi.org/10.1261/rna.051102.115