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O6-Methylguanosine leads to position-dependent effects on ribosome speed and fidelity
Nucleic acids are under constant assault from endogenous and environmental agents that alter their physical and chemical properties. O6-methylation of guanosine (m(6)G) is particularly notable for its high mutagenicity, pairing with T, during DNA replication. Yet, while m(6)G accumulates in both DNA...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536324/ https://www.ncbi.nlm.nih.gov/pubmed/26199454 http://dx.doi.org/10.1261/rna.052464.115 |