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The GABA(A) antagonist bicuculline attenuates progesterone-induced memory impairments in middle-aged ovariectomized rats

In women, high levels of natural progesterone have been associated with detrimental cognitive effects via the “maternal amnesia” phenomenon as well as in controlled experiments. In aged ovariectomized (Ovx) rats, progesterone has been shown to impair cognition and impact the GABAergic system in cogn...

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Detalles Bibliográficos
Autores principales: Braden, B. Blair, Kingston, Melissa L., Koenig, Elizabeth N., Lavery, Courtney N., Tsang, Candy W. S., Bimonte-Nelson, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536389/
https://www.ncbi.nlm.nih.gov/pubmed/26321945
http://dx.doi.org/10.3389/fnagi.2015.00149