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The equatorial position of the metaphase plate ensures symmetric cell divisions

Chromosome alignment in the middle of the bipolar spindle is a hallmark of metazoan cell divisions. When we offset the metaphase plate position by creating an asymmetric centriole distribution on each pole, we find that metaphase plates relocate to the middle of the spindle before anaphase. The spin...

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Detalles Bibliográficos
Autores principales: Tan, Chia Huei, Gasic, Ivana, Huber-Reggi, Sabina P, Dudka, Damian, Barisic, Marin, Maiato, Helder, Meraldi, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536468/
https://www.ncbi.nlm.nih.gov/pubmed/26188083
http://dx.doi.org/10.7554/eLife.05124