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The phospholipid-binding protein SESTD1 negatively regulates dendritic spine density by interfering with Rac1-Trio8 signaling pathway

Dendritic spines are actin-rich protrusions from neuronal dendrites that harbor the majority of excitatory synapses. The balance of spine formation and retraction may influence dendritic integrity. While knowledge of the molecular mechanisms that promote dendritic spine formation has accumulated, li...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Che, Huang, Chiung-Chun, Hsu, Kuei-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536496/
https://www.ncbi.nlm.nih.gov/pubmed/26272757
http://dx.doi.org/10.1038/srep13250