Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer

BACKGROUND: Epigenetic changes are being increasingly recognized as a prominent feature of cancer. This occurs not only at individual genes, but also over larger chromosomal domains. To investigate this, we set out to identify large chromosomal domains of epigenetic dysregulation in breast cancers....

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Detalles Bibliográficos
Autores principales: Rafique, Sehrish, Thomas, Jeremy S., Sproul, Duncan, Bickmore, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536608/
https://www.ncbi.nlm.nih.gov/pubmed/26235388
http://dx.doi.org/10.1186/s13059-015-0719-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536608/
https://www.ncbi.nlm.nih.gov/pubmed/26235388
http://dx.doi.org/10.1186/s13059-015-0719-9

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