Lentiviral shRNA against KCa3.1 inhibits allergic response in allergic rhinitis and suppresses mast cell activity via PI3K/AKT signaling pathway

Calcium-activated potassium ion channel-3.1 (KCa3.1) plays a pivotal role in the potassium-calcium exchange involved in atopy. This study aimed to explore the impact of lentiviral-mediated shRNA silencing KCa3.1 on allergic response in a murine allergic rhinitis (AR) model. The BALB/c mice were divi...

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Detalles Bibliográficos
Autores principales: Lin, Hai, Zheng, Chunquan, Li, Jing, Yang, Chen, Hu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536635/
https://www.ncbi.nlm.nih.gov/pubmed/26272420
http://dx.doi.org/10.1038/srep13127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536635/
https://www.ncbi.nlm.nih.gov/pubmed/26272420
http://dx.doi.org/10.1038/srep13127

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