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The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

Understanding the initiation and progression of pancreatic ductal adenocarcinoma (PDAC) may provide therapeutic strategies for this deadly disease. Recently, we and others made the surprising finding that PDAC and its preinvasive precursors, pancreatic intraepithelial neoplasia (PanIN), arise via re...

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Detalles Bibliográficos
Autores principales: Krah, Nathan M, De La O, Jean-Paul, Swift, Galvin H, Hoang, Chinh Q, Willet, Spencer G, Chen Pan, Fong, Cash, Gabriela M, Bronner, Mary P, Wright, Christopher VE, MacDonald, Raymond J, Murtaugh, L Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536747/
https://www.ncbi.nlm.nih.gov/pubmed/26151762
http://dx.doi.org/10.7554/eLife.07125