Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial

BACKGROUND: We compared adjunctive treatment with placebo, dexamethasone, anti-C5 antibodies, and the combination of dexamethasone plus anti-C5 antibodies in experimental pneumococcal meningitis. METHODS: In this prospective, investigator-blinded, randomized trial, 96 mice were infected intracistern...

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Detalles Bibliográficos
Autores principales: Kasanmoentalib, E. Soemirien, Valls Seron, Mercedes, Morgan, B. Paul, Brouwer, Matthijs C., van de Beek, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536776/
https://www.ncbi.nlm.nih.gov/pubmed/26272468
http://dx.doi.org/10.1186/s12974-015-0372-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536776/
https://www.ncbi.nlm.nih.gov/pubmed/26272468
http://dx.doi.org/10.1186/s12974-015-0372-y

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