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Getting the genome in shape: the formation of loops, domains and compartments
The hierarchical levels of genome architecture exert transcriptional control by tuning the accessibility and proximity of genes and regulatory elements. Here, we review current insights into the trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536798/ https://www.ncbi.nlm.nih.gov/pubmed/26257189 http://dx.doi.org/10.1186/s13059-015-0730-1 |