Cargando…

Cabozantinib, a Novel c-Met Inhibitor, Inhibits Colorectal Cancer Development in a Xenograft Model

BACKGROUND: Angiogenesis plays a critical role during tumor development. c-Met has recently been implicated in the angiogenesis of various tumors, leaving its role in colorectal cancer (CRC) unknown. In this study, we aimed to evaluate the effect of a novel c-Met inhibitor, cabozantinib, on the tumo...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yinggang, Sun, Liyong, An, Yanxin, Shen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536870/
https://www.ncbi.nlm.nih.gov/pubmed/26255947
http://dx.doi.org/10.12659/MSM.893590