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Macrophages promote renal fibrosis through direct and indirect mechanisms

There is a close spatial and temporal relationship between macrophage accumulation and active renal fibrosis in human and experimental kidney disease. Different subtypes of macrophages have been identified. Pro-inflammatory M1-type macrophages can cause acute tissue injury, whereas pro-fibrotic M2-t...

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Detalles Bibliográficos
Autores principales: Nikolic-Paterson, David J, Wang, Shuang, Lan, Hui Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536961/
https://www.ncbi.nlm.nih.gov/pubmed/26312148
http://dx.doi.org/10.1038/kisup.2014.7