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Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment

As we age, the homeostatic function of many systems in the body, such as the immune function declines, which in turn contributes to augment susceptibility to disease. Here we describe that challenging aged mice with synthetic oligodeoxynucleotides containing unmethylated cytosine guanine motifs (CpG...

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Detalles Bibliográficos
Autores principales: Harman, María F., Ranocchia, Romina P., Gorlino, Carolina V., Sánchez Vallecillo, María F., Castell, Sofía D., Crespo, María I., Maletto, Belkys A., Morón, Gabriel, Pistoresi-Palencia, María C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537026/
https://www.ncbi.nlm.nih.gov/pubmed/25922914