YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

Specific overexpression in cancer cells and evidence of oncogenic functions make Survivin an attractive target in cancer tharapy. The small molecule compound YM155 has been described as the first “Survivin suppressant” but molecular mechanisms involved in its biological activity and its clinical pot...

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Detalles Bibliográficos
Autores principales: Véquaud, Eloïse, Séveno, Céline, Loussouarn, Delphine, Engelhart, Lucie, Campone, Mario, Juin, Philippe, Barillé-Nion, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537028/
https://www.ncbi.nlm.nih.gov/pubmed/25974963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537028/
https://www.ncbi.nlm.nih.gov/pubmed/25974963

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