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Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon

The focal adhesion protein leupaxin (LPXN) is overexpressed in a subset of prostate cancers (PCa) and is involved in the progression of PCa. In the present study, we analyzed the LPXN-mediated adhesive and cytoskeletal changes during PCa progression. We identified an interaction between the actin-bi...

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Detalles Bibliográficos
Autores principales: Dierks, Sascha, von Hardenberg, Sandra, Schmidt, Thomas, Bremmer, Felix, Burfeind, Peter, Kaulfuß, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537036/
https://www.ncbi.nlm.nih.gov/pubmed/26079947