Enhanced tumorigenicity by mitochondrial DNA mild mutations

To understand how mitochondria are involved in malignant transformation we have generated a collection of transmitochondrial cybrid cell lines on the same nuclear background (143B) but with mutant mitochondrial DNA (mtDNA) variants with different degrees of pathogenicity. These include the severe mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Cruz-Bermúdez, Alberto, Vallejo, Carmen G., Vicente-Blanco, Ramiro J., Gallardo, María Esther, Fernández-Moreno, Miguel Ángel, Quintanilla, Miguel, Garesse, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537038/
https://www.ncbi.nlm.nih.gov/pubmed/25909222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537038/
https://www.ncbi.nlm.nih.gov/pubmed/25909222

Ejemplares similares