The Human Myotrophin Variant Attenuates MicroRNA-Let-7 Binding Ability but Not Risk of Left Ventricular Hypertrophy in Human Essential Hypertension

Myotrophin, known as a myocardial hypertrophy-inducing factor, is responsible for the initiation of cardiac hypertrophy that transits to heart failure. MicroRNAs are small noncoding RNAs that down-regulate posttranscriptional expression of target molecules. We investigated the role of variants of th...

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Detalles Bibliográficos
Autores principales: Wang, Yuyao, Chen, Jingzhou, Song, Weihua, Wang, Yuxuan, Chen, Yu, Nie, Yu, Hui, Rutai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537090/
https://www.ncbi.nlm.nih.gov/pubmed/26274321
http://dx.doi.org/10.1371/journal.pone.0135526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537090/
https://www.ncbi.nlm.nih.gov/pubmed/26274321
http://dx.doi.org/10.1371/journal.pone.0135526

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