Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production

Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear. Direct antiviral activity and immunomodulatory functions h...

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Detalles Bibliográficos
Autores principales: Wang, Yang, McGivern, David R, Cheng, Liang, Li, Guangming, Lemon, Stanley M, Niu, Junqi, Su, Lishan, Reszka-Blanco, Natalia J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537094/
https://www.ncbi.nlm.nih.gov/pubmed/26274905
http://dx.doi.org/10.1371/journal.pone.0135232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537094/
https://www.ncbi.nlm.nih.gov/pubmed/26274905
http://dx.doi.org/10.1371/journal.pone.0135232

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