LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice

The LKB1 gene, which encodes a serine/threonine kinase, was discovered to play crucial roles in cell differentiation, proliferation, and the establishment of cell polarity. In our study, LKB1 conditional knockout mice (Atoh1-LKB1(-/-) mice) were generated to investigate LKB1 function in the inner ea...

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Detalles Bibliográficos
Autores principales: Men, Yuqin, Zhang, Aizhen, Li, Haixiang, Zhang, Tingting, Jin, Yecheng, Li, Huashun, Zhang, Jian, Gao, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537123/
https://www.ncbi.nlm.nih.gov/pubmed/26274331
http://dx.doi.org/10.1371/journal.pone.0135841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537123/
https://www.ncbi.nlm.nih.gov/pubmed/26274331
http://dx.doi.org/10.1371/journal.pone.0135841

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