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LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice
The LKB1 gene, which encodes a serine/threonine kinase, was discovered to play crucial roles in cell differentiation, proliferation, and the establishment of cell polarity. In our study, LKB1 conditional knockout mice (Atoh1-LKB1(-/-) mice) were generated to investigate LKB1 function in the inner ea...
Autores principales: | Men, Yuqin, Zhang, Aizhen, Li, Haixiang, Zhang, Tingting, Jin, Yecheng, Li, Huashun, Zhang, Jian, Gao, Jiangang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537123/ https://www.ncbi.nlm.nih.gov/pubmed/26274331 http://dx.doi.org/10.1371/journal.pone.0135841 |
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