Prognostic Significance of Nuclear Phospho-ATM Expression in Melanoma

UV radiation induced genomic instability is one of the leading causes for melanoma. Phosphorylation of Ataxia Telangiectasia Mutated (ATM) is one of the initial events that follow DNA damage. Phospho-ATM (p-ATM) plays a key role in the activation of DNA repair and several oncogenic pathways as well...

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Detalles Bibliográficos
Autores principales: Bhandaru, Madhuri, Martinka, Magdalena, McElwee, Kevin J., Rotte, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537129/
https://www.ncbi.nlm.nih.gov/pubmed/26275218
http://dx.doi.org/10.1371/journal.pone.0134678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537129/
https://www.ncbi.nlm.nih.gov/pubmed/26275218
http://dx.doi.org/10.1371/journal.pone.0134678

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