Cargando…

Prognostic Significance of Nuclear Phospho-ATM Expression in Melanoma

UV radiation induced genomic instability is one of the leading causes for melanoma. Phosphorylation of Ataxia Telangiectasia Mutated (ATM) is one of the initial events that follow DNA damage. Phospho-ATM (p-ATM) plays a key role in the activation of DNA repair and several oncogenic pathways as well...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhandaru, Madhuri, Martinka, Magdalena, McElwee, Kevin J., Rotte, Anand
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537129/ https://www.ncbi.nlm.nih.gov/pubmed/26275218 http://dx.doi.org/10.1371/journal.pone.0134678

Ejemplares similares

A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma
por: Bhandaru, Madhuri, et al.
Publicado: (2014)

Decreased Expression of Nuclear p300 Is Associated with Disease Progression and Worse Prognosis of Melanoma Patients
por: Rotte, Anand, et al.
Publicado: (2013)

Stage-specific prognostic biomarkers in melanoma
por: Cheng, Yabin, et al.
Publicado: (2015)

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma
por: Guo, Hongwei, et al.
Publicado: (2015)

Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis
por: Zhang, Guohong, et al.
Publicado: (2015)

Nobel committee honors tumor immunologists
por: Rotte, Anand, et al.
Publicado: (2018)

Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma
por: Khosravi, Shahram, et al.
Publicado: (2016)

Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma
por: LU, JING, et al.
Publicado: (2015)

Nuclear ING2 expression is reduced in human cutaneous melanomas
por: Lu, F, et al.
Publicado: (2006)

Expression of Phospho-ELK1 and Its Prognostic Significance in Urothelial Carcinoma of the Upper Urinary Tract
por: Inoue, Satoshi, et al.
Publicado: (2018)

Addressing the age-old question of old age
por: McElwee, Joshua J
Publicado: (2004)

The Selection of Candidates for Trade School from a Group of Subnormal Italian Girls
por: McElwee, Edna Willis
Publicado: (1932)

An Analysis of the Binet Test of Naming Words
por: McElwee, Edna Willis
Publicado: (1932)

A Study of the Reading Attainment of Children in Ungraded Classes
por: McElwee, Edna Willis
Publicado: (1931)

C-Terminal Tensin-Like Protein Is a Novel Prognostic Marker for Primary Melanoma Patients
por: Sjoestroem, Cecilia, et al.
Publicado: (2013)

Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma
por: Jafarnejad, Seyed Mehdi, et al.
Publicado: (2013)

Cytoplasmic Skp2 Expression Is Increased in Human Melanoma and Correlated with Patient Survival
por: Chen, Guangdi, et al.
Publicado: (2011)

The prognostic significance of heparanase expression in metastatic melanoma
por: Vornicova, Olga, et al.
Publicado: (2016)

Sox4 Mediated Dicer Expression is Critical for Suppression of Melanoma Cell Invasion
por: Jafarnejad, Seyed Mehdi, et al.
Publicado: (2012)

Formylation of Amines
por: Gerack, Ciera J., et al.
Publicado: (2014)

Clinicopathologic significance of nuclear HER4 and phospho-YAP(S(127)) in human breast cancers and matching brain metastases
por: Kalita-de Croft, Priyakshi, et al.
Publicado: (2020)

Prognostic significance of the aberrant expression of neuroendocrine markers in melanomas
por: Wu, Yan, et al.
Publicado: (2021)

Expression and clinical significance of ATM and PUMA gene in patients with colorectal cancer
por: Xiong, Hui, et al.
Publicado: (2017)

Phospho-AXL is widely expressed in glioblastoma and associated with significant shorter overall survival
por: Onken, Julia, et al.
Publicado: (2017)

Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosis
por: Chen, Xin, et al.
Publicado: (2018)

Reduced Apaf-1 expression in human cutaneous melanomas
por: Dai, D L, et al.
Publicado: (2004)

Hypothesis Testing: CTLA4 Co-stimulatory Pathways Critical in the Pathogenesis of Human and Mouse Alopecia Areata
por: Sundberg, John P., et al.
Publicado: (2011)

Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression
por: Di Benedetto, Anna, et al.
Publicado: (2017)

Structure of the herpes simplex virus portal-vertex
por: McElwee, Marion, et al.
Publicado: (2018)

ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels
por: Shah, Pragya, et al.
Publicado: (2022)

Prognostic role of phospho-PRAS40 (Thr246) expression in gastric cancer
por: Lu, Yi-Zhuo, et al.
Publicado: (2013)

ING4 regulates JWA in angiogenesis and their prognostic value in melanoma patients
por: Lu, J, et al.
Publicado: (2013)

Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis
por: Shi, Feng-Tao, et al.
Publicado: (2017)

Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies
por: Hao, Ke, et al.
Publicado: (2009)

Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species
por: Hall, Julie A., et al.
Publicado: (2017)

SAT-LB113 Psychosocial Benefits of Using Basal-IQ® Predictive Low Glucose Suspend Technology in a Real-World Setting: Results From Pediatric Patients With Type 1 Diabetes
por: Singh, Harsimran, et al.
Publicado: (2020)

Virtual Pump Trainings for the t:slim X2 Insulin Pump With Control-IQ Advanced Hybrid Closed-Loop Technology: Real World Patient Experience
por: Singh, Harsimran, et al.
Publicado: (2021)

Expression and prognostic relevance of MET and phospho-BAD in non-small cell lung cancer
por: Sun, Wenze, et al.
Publicado: (2013)

In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography
por: Vijayakrishnan, Swetha, et al.
Publicado: (2020)

Accuracy of death certifications of diabetes, dementia and cancer in Australia: a population-based cohort study
por: Xu, Zhiwei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u67ua5ohg0c7d824a6m4a1r31o