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Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines

Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific anticholinesterase), but does not directly address th...

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Detalles Bibliográficos
Autores principales: Ring, Avi, Strom, Bjorn Oddvar, Turner, Simon R., Timperley, Christopher M., Bird, Michael, Green, A. Christopher, Chad, John E., Worek, Franz, Tattersall, John E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537131/
https://www.ncbi.nlm.nih.gov/pubmed/26274808
http://dx.doi.org/10.1371/journal.pone.0135811